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Other non-invasive surrogates for evaluating the Ees/Ea ratio in the context of RV-PA coupling include FAC, as well as the FAC/mPAP and TAPSE/PA-AT ratios 20

Generally well-tolerated: Clinical trials report good safety profiles with parenteral L-Carnitine, even at high doses (up to 50 mg/kg IV daily) [5] [8]

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